【佳學基因檢測】不孕不育與生殖缺陷專家:張愛軍教授
遺傳病、罕見病基因檢測導讀:
張愛軍,教授, 國際有很高知名度生殖專家。擅長卵母細胞漿內(nèi)單精子注射、體外受精-胚胎移植、胚胎活檢、胚胎冷凍、自存精子冷凍等各項輔助生殖技術實驗室技術?,F(xiàn)任上海交通大學附屬瑞金醫(yī)院婦產(chǎn)科學博士生導師。
張愛軍教授簡介:
張愛軍,生殖醫(yī)學中心實驗室主任,副主任技師,1998年畢業(yè)于山東大學生命科學院細胞及分子生物學專業(yè)。從事人類輔助生殖技術實驗室工作至今,掌握胚胎學、生殖醫(yī)學、遺傳學等專業(yè)理論知識,熟練卵母細胞漿內(nèi)單精子注射、體外受精-胚胎移植、胚胎活檢、胚胎冷凍、自存精子冷凍等各項輔助生殖技術實驗室技術。作為主要技術骨干,早期參與了瑞金醫(yī)院生殖醫(yī)學中心的設計和籌建;中心建成之后,認真完成實驗室各項質(zhì)控工作,同時培訓相關技術人員,為順利開展臨床工作奠定了良好的基礎。在迎接衛(wèi)生部專家的評審與復評審工作中,盡職盡責,使生殖醫(yī)學中心順利通過衛(wèi)生部的檢查,獲得開展人類輔助生殖技術的資質(zhì)做出了突出貢獻。工作中建立了系統(tǒng)有效的實驗室質(zhì)控程序和嚴格的胚胎發(fā)育潛能評估系統(tǒng),取得了良好的臨床效果。平時積極配合臨床,開展新技術、新項目,不斷豐富臨床診斷資料,其中改良機械法輔助孵化透明帶切口方式改善卵母細胞漿內(nèi)單精子注射方式的研究,作為新技術分別在中華醫(yī)學成立大會和亞洲男科學大會上交流。曾先后到新加坡國立大學和香港中文大學生殖中心參觀學習。作為課題負責人,目前承擔上海市科委自然基金課題1項;作為主要研究人員,參與國家自然基金和上海市科委重大課題各1項,近3年在國家核心期刊發(fā)表相關學術論文10余篇。曾獲2004年度瑞金醫(yī)院先進員工獎。
張愛軍教授究方向
人類種植前胚胎發(fā)育潛能及子宮內(nèi)膜容受性
張愛軍教授社會任職
張愛軍教授在國際生殖領域的研究領域:
張愛軍教授對國際生殖領域及出生缺陷的貢獻
- Huihui Xu, Mingjuan Zhou, Yi Cao, Dan Zhang, Mi Han, Xinxing Gao, Bufang Xu, Aijun Zhang (通訊作者) Genome-wide analysis of long noncoding RNAs, microRNAs, and mRNAs forming a competing endogenous RNA network in repeated implantation failure Gene 2019 /
- Dan Zhang, Lan Xia, Huihui Xu, Qian Chen, Bailing Jin, Aijun Zhang* and Bufang Xu* (通訊作者) Flexible Low-Dose GnRH Antagonist Protocol Is Effective in Patients With Sufficient Ovarian Reserve in IVF Frontiers in Endocrinology 2019 9:767-7
- Xiaoyu Xia#, Xiaowei Zhou#, Yanmei Quan#, Yanqin Hu, Fengying Xing, Zhengzheng Li, Bufang Xu*, Chen Xu* and Aijun Zhang* Germline deletion of Cdyl causes teratozoospermia and progressive infertility in male mice Cell Death and Disease 2019 10:229-13
- Wen-Jie Zhou, Jie Zhang, Hui-Li Yang, Ke Wu, Feng Xie, Jiang-Nan Wu, Yan Wang, Li Yao, Yan Zhuang,Jiang-Dong Xiang, Ai-Jun Zhang* (通訊作者), Yin-Yan He* and Ming-Qing Li* Estrogen inhibits autophagy and promotes growth of endometrial cancer by promoting glutamine metabolism Cell Communication and Signaling 2019 17:99-15
- Jin Bailing, Niu Zhihong, Xu Bufang, Chen Qian, Zhang Aijun (通訊作者) comparison of clinical outcomes among dual ovarian stimulation, mild stimulation and luteal phase stimulation protocols in women with poor ovarian response Gynecol Endocrinol 2018 34(8) :694-697
- F Guo, C Si, M Zhou, J Wang, D Zhang, Leung PCK, B Xu,Zhang A (通訊作者) Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure 《Human Reproduction》 2018 33 (5) :832-843
- B Xu, M Zhou, J Wang, D Zhang, F Guo, Si C, Leung PCK, Zhang A (通訊作者) Increased AIF-1-mediated TNF-α expression during implantation phase in IVF cycles with GnRH antagonist protocol 《Human Reproduction》 2018 33 (7):1270-1280
- Bufang Xu1,*, Jingwen Wang1,*, Lan Xia1, Dan Zhang1 (通訊作者), Xian Wu1 & Aijun Zhang1,2 GnRH antagonist negatively affects endometrial receptivity in in vitro fertilization (IVF) cycles, however, its underlying mechanism remains unclear. 《Scientific Reports》 2017 3(7):39912
- N.Zhihong,F.Yun,Z.Pinggui,Z.Sulian,Aijun Zhang (通訊作者) Cytokine profiling in the Eutopin Endometrium of Adenomyosis During the Implantation Window after Ovarian Stimulation Reproductive Sciences 2016 23(1):124-133
- 李雁,葉瑤,徐步芳,張愛軍 (通訊作者) 抗神經(jīng)生長隱私抗體用于改善子宮腺肌病小鼠宮腔內(nèi)環(huán)境的研究 生殖與避孕 2015 35(6):353-358
- Qian Chen, Aijun Zhang (共同先進作者),Feng Yu,Jing Gao,Yue Liu,Chenli Yu,Xu Zhou,Chen Xu Label-Free Proteomics Uncovers Energy Metabolism and Focal Adhesion Regulations Responsive for Endometrium Receptivity proteome research 2015 14,1831-1842
- Bu-fang Xu,Guang-yan Wang,Wei-min Fan,Qian Chen, Ai-jun Zhang (通訊作者) Which is the Best Protocol of Ovarian Stimulation Prior to Artificial Insemination by Donor Sperm. Journal of Reproduction & Contraception Journal of Reproduction & Contraception 2014 25(1):41-48
- Ling Wu, Bufang Xu, Weimin Fan, Xiaobin Zhu, Guangyan Wang, Aijun zhang (通訊作者), Adiponectin protects Leydig cells against pro-inflammatory cytokines by suppressing the nuclear factor-kappaB signaling pathway FEBS Journal 2013 280(16):3920-7
- Wu L, Zhang A, Sun Y, Zhu X, Fan W, Lu X, Yang Q, Feng Y Sirt1 exerts anti-inflammatory effects and promotes steroidogenesis in Leydig cells Fertil Steril 2012 98(1):194-9
- Aijun Zhang, Bufang Xu, Yijuan Sun, Xiaowei Lu, Ruihuan Gu, Qian Chen, Yun Feng, Chen Xu The effect of human cumulus cells on the maturation and developmental potential of immature oocytes in ICSI cycles. J Assist Reprod Genet 2012 29:313-9
- 朱曉斌,馮云,吳玲,樊衛(wèi)民,陸小溦,孫貽娟,谷瑞環(huán),張愛軍 (通訊作者) 自精保存在輔助生殖技術中的意義 中國優(yōu)生與遺傳雜志 2012 20(3):118-9
- Bufang Xu, Xiaoxi Sun, Lu Li, Ling Wu, Aijun Zhang (通訊作者), Yun Feng Pinopodes, leukemia inhibitory factor, integrin-b3, and mucin-1 expression in the peri-implantation endometrium of women with unexplained recurrent pregnancy loss Fertil Steril 2012 98(2):389-95
- 朱曉斌,馮云,楊青青,陸小溦,樊衛(wèi)民,吳鈴,李志超,張愛軍 (通訊作者) 染色體異常對IVF-ET妊娠結局的影響 中國男科學雜志 2012 26(10):29-32
- Sun Y, Feng Y, Zhang A, Lu X, Niu Z, Gu R Frozen-thawed embryo transfer cycles in China: clinical outcomes of two and three multicellular embryos transfers J Assist Reprod Genet 2012 29(5):417-21
- Aijun Zhang, Bufang Xu, Yijuan Sun, Xiaowei Lu, Ruihuan Gu, Ling Wu, Yun Feng, Chen Xu Dynamic changes of histone H3 trimethylated at positions K4 and K27 in human oocytes and pre-implantation embryos Fertil Steril 2012 98(4):1009-16
- 徐步芳, 孫貽娟,陸小溦,朱曉斌,馮云,張愛軍 (通訊作者) 精子DNA碎片率對常規(guī)體外受精-胚胎移植結局的影響 中國男科學雜志 2011 25(8):23-26
- 谷瑞環(huán),孫貽娟,陸小溦,馮云,張愛軍 (通訊作者) 第二極體排出時間在預測體外受精結局中的價值 中華臨床醫(yī)師雜志 2011 5(14):4127-32
- 徐步芳,馮云,王楓釗,牛志宏,陳騫,張愛軍 (通訊作者) 胚胎移植日子宮內(nèi)膜運動波對凍融胚胎移植周期妊娠結局的預測價值 中華臨床醫(yī)師雜志 2011 5(14):32-5
- 朱曉斌, 馮云, 紀冬梅, 劉建兵, 徐步芳, 張愛軍 (通訊作者) Y染色體微缺失檢測及生激素水平研究在非梗阻性無精子癥患者睪丸穿刺中的意義 中國男科學雜志 2010 24(2):35-38
- 紀冬梅, 馮云, 李錚, 朱曉斌, 張愛軍 (通訊作者) 810例嚴重少(無)精子癥患者Y染色體微缺失篩查與分析 中國優(yōu)生與遺傳雜志 2010 18(2):36-38
- Qian CHEN, Ai-jun ZHANG (通訊作者), Yun FENG, Xiao-wei LU, Dong-mei JI, Zhi-peng XU Effect of the P1 Medium and the ECM Medium on Embryo Journal of Reproduction & Contraception 2009 20(2):22-7
- 孫貽娟,張愛軍 (通訊作者),馮 云, 張慧琴,牛志宏,陸小溦 不同胚胎選擇體系對體外受精-胚胎移植妊娠結局的影響 生 殖 與 避 孕 2009 29(1):26-30
- Niu Z, Feng Y, Zhang A, Sun Y, Zhang H Progesterone levels on oocyte retrieval day can predict the quantity of viable embryos but not pregnancy outcome of intracytoplasmic sperm injection Gynecol Endocrinol 2008 24(8):452-8
- 李雁, 馮云, 孫貽娟, 牛志宏, 張愛軍 (通訊作者) 人卵母細胞與體細胞的電融合效率 上海交通大學學報( 醫(yī)學版) 2007 27:837-840 本文的目的只是起傳播知識的目的,不代表本網(wǎng)站有效認同本文的觀點,不暗示或者說明文中內(nèi)容與人物與佳學基因存在任何關系。