【佳學(xué)基因檢測】基因調(diào)控網(wǎng)絡(luò)：分析乳腺癌發(fā)生、發(fā)展與藥物反應(yīng)的新概念框架

全國十大基因檢測公司排名簡介

研討《腫瘤致病基因突變位點(diǎn)的性質(zhì)及影響分析》時(shí)，發(fā)現(xiàn)《Ann Oncol》在 2011 Jun;22(6):1259-1265發(fā)表了一篇題目為《基因調(diào)控網(wǎng)絡(luò)：分析乳腺癌行為的新概念框架》腫瘤靶向藥物治療基因檢測臨床研究文章。該研究由R Demicheli, D Coradini 等完成。促進(jìn)了基因突變解碼及基因背景對乳腺癌發(fā)生發(fā)展的影響，進(jìn)一步強(qiáng)調(diào)了基因信息檢測與分析的重要性。

腫瘤靶向藥物及正確治療臨床研究內(nèi)容關(guān)鍵詞：

基因調(diào)控,網(wǎng)絡(luò),乳腺癌,行為,新概念,框架

腫瘤靶向治療基因檢測臨床應(yīng)用結(jié)果

對復(fù)雜系統(tǒng)的研究清楚地證明，一些整體行為屬性不能從它們單個(gè)部分的屬性中推斷出來，而是由它們的架構(gòu)決定的。賊近在生物學(xué)中提出了這種方法以了解基因組功能，并在腫瘤學(xué)中提出了對各種癌癥行為的更一致的解釋。從目前的角度來看，我們總結(jié)了所提出的全局方法的基本概念，然后在這個(gè)新的背景下重新考慮腫瘤休眠和原發(fā)性腫瘤切除效應(yīng)，這賊近成為理解乳腺癌的關(guān)鍵點(diǎn)。

腫瘤發(fā)生與反復(fù)轉(zhuǎn)移國際數(shù)據(jù)庫描述：

The study of complex systems has clearly evidenced that a few overall behavioural properties cannot be inferred from the properties of their single parts and are rather determined by their architecture. Such an approach has been recently proposed in biology to understand genome functioning and in oncology to endeavour a more consistent explanation of the variegated cancer behaviours. In the present perspective, we summarise the basic concepts of the proposed global approach and then we reconsider, in this new context, tumour dormancy and primary tumour removal effects, which recently emerged as critical points for breast cancer understanding.